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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13a7e696bb03ec68fcc39932f3ba7785b89562c77a8a1d327a4d2f791b72c2ed' 
  AND token = 'FSQA/JkIq6hu2b2K4xrtp7qLsBvYWSapCyVhMjSP2Fc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}