SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66dc4f5a7e25afe53bd09ee0a716e63eab93f9d3140f8b397de60ad794ee3559' 
  AND token = 'C6eQm5EM00GB968g0lpd75VIeOtaHjQxeKbVcicPKho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}