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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '861fce7de8dcd1a7b44f481bf25f264f247416fba4020f4e707cdf0220189258' 
  AND token = '4GWuuxpdBmjpVk6BxHtv3Ow066bQIj6rf0HUwE2cyCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}