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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a579bd13de404d8847a217f9d2145af7c0027a8311abfe179a1453de538fe534' 
  AND token = 'yvcSEo6z7d8ex0AZZWou/CpMkYcx1iPB/ARy+G0XiVA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}