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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ea5a539813947b9127303ecedff183501144a08fc24d961f6a2ca11579c54c1' 
  AND token = '7f1x1uDy6x/PQ6hIo7nV2AgZiD+CmqH28HkNvhQESh0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}