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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '499c2d3d6d6770c4a95d1f7dab9a8d7013a0a87cb65bcf159e6c9c8a9bdc1636' 
  AND token = 'O+Olqhh1AAKx5mRcEnPZROrGaOukWnmaELgOVVNFrvo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}