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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1dea90b6cad689bd27c1ec391abd13873e212286d3fc491d007a2bfd0a284a8' 
  AND token = 'P2I3ddnEGE3+oXtxY1hZNAV2Q23Sd0VLLyHaTIRWmO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}