SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b529c00768fb2396076f8a073d5d22580615ea55c49bd488fd4eb5c3e94d259' 
  AND token = 'Y3q7uIFRN0nMW5fh/Xqwi4mP7xooOFRhnPqknI0U6tY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00062

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}