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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b59f0f69a0220bbc89bf5cb67d78c94470a7b0c818614ed15c65a84241c43732' 
  AND token = 'QFIAaLx9TAMWkwTu/W09F2HW91NSZDYUJb3kTYOl/90=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}