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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bf0b060e090868e18cf25e8937e2da6a1f676e21c9f3bd460bbb019d996f84c6' 
  AND token = 'BwmogohdpCLh3IfT05BtapuK7SUNCCSG1gGdIn0twnc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}