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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e05b7ed5766eac90be677ef7e1bd5c1e3be86f49cd1e4cdb77948a42a88c95e' 
  AND token = 'yVkJcB44pmknGtGOtMaokULBsd3ueGgldKqJ5iY2wnM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}