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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c2913212ada8d9a45ac1a7b36666876745bef3a28b0731300863c2717c85dec' 
  AND token = 'TrAxxyI1wy50DFLLLGSrzCrLaNbdNHALDw0mOnO8c1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}