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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '168ab6ec1f07f5a0256d0572e2a4fba3ab2f8f129272914e51885d453b95c557' 
  AND token = '8zZUwfksShZb9Qbb7rFWsGZE3sJyLohpR4/o2v++HTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}