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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b43a92f04d776184bb9822f17f2afb5f8f3ff36317680bf553c662723d65a41' 
  AND token = 'z2HThirvT2mgTJ0ElIEY0sO6rq4LL6p+ue8+Pav7tO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}