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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45c9d16555b2a6d8bfbefd8a5c6366fe01a430769c9afe28c3314fc6ad4a3c53' 
  AND token = 'FgVM/lUfjhHpD0BmGRId0V2ij7d16EtABl46H7FAyKk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}