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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f201d86d1c8dc38b836d32bd023d9f45a98383d817c80a2731a1dc0030dbf6a6' 
  AND token = 't3TBxt62rqTn06Fow0vl785lCP5AyvUKnrG7RrJvnyU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}