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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19bd7bf2a9b4b92450cf1388dc968d4e8270e28d5076aa8f5b5f2b106480a320' 
  AND token = 'lOtiCbQTDlKOLD6MHXEsIECNsZ8TQNzE8eihkcrv8SU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}