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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '376c8e45a041f6907fe3d7e88b64efc336f885596f9f183d340fedd4cbc8f520' 
  AND token = 'Qc6ClQ/762tkifJDeXYbGnNQVpRXAgI3cIAzNKViG/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}