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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff26c0c96ec2762ba94f3d6dbf94603331ce4692fb49df271d90cceef3edb78e' 
  AND token = 'W39MqaXUjaMiwdVJ+TfwsVmHo479aDcGv14gexW5mDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}