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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33ec442e8a17267a35e4b22d98d16d6c1e81425a1f95dff13d4605426c5b2807' 
  AND token = 'S5Fx5O0T63xlvX9zZVzFtHuo6A5EBsYJNTbgk7Y1xe0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}