SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee4875c2c7a4e8ec5605ad7af97df2fe244c407c91e8050db70a579d371dc688' 
  AND token = 'e17ivicTKHc890h/KCVZUCAEN8sDcOoHJ+CcgUnlnKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}