SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2291b1bbc93f3de5616edbee61fae64b845320e280eabc6157cc1650d4f78d98' 
  AND token = 'QXhc/F0PSpoMpAXEHnf8tZT7FCKywxHOwlCCjdeGLQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}