SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1d54f3b177f3d8948d778589c06d6b7542e515fc1185127b24fcce0525cd748' 
  AND token = 'I+VlQT5ycTkWn2KXvdOJvtHhu33abwxzQ0kZarFQYek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}