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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b43cb8fcc3213628673da0347e5c9210b93521eaf807c4fff7e1248b5da6936' 
  AND token = '1569wEGo2lMXsGyuCe4Il2G/ThP45Avha+iVGdqZyXA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}