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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e03d23c201b623bea8af6e81b0f662a75765a202f6cf7668d8026833ac2e2269' 
  AND token = 'YDD6SM9HDXqL6FIZ1m/rNOvoQ+ncR+nVj84CH9hqd6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}