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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45a63ce27602d2227665ff5a3c7d728c3dbd51e22652db6cb8aa0e8af7b51af6' 
  AND token = 'jI9Cc3pcmlFNn+sKZcUjJ5DgnOFTmOrKrULeHhDIG9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}