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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38cf0b8535931eddf7c7fb6bff2ad366d4c16d839e86d7895b69c40bae4e21e2' 
  AND token = 'PNlEVd3GD+g/WAMeD10N6pRgKAuDzi6pw9vJoMwA98E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}