SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04ad448f9fbd2d4b7e540e9a9c6e958b8e9f152c50323873defd470ebd7a71e0' 
  AND token = 'DMYhUYI1YARz1KcoQbIAptT8lNg+U7zt2bFwy9kicCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}