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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25f5e10029e898834d2113b108d68b32e1b8b3dd46ca6a53b75a9d3703d9fdbd' 
  AND token = 'zzfpWRtacR/u7gP37x9yoKcq2HD1PAnyh2H4HtncCuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}