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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '980e9da2160e92174446abaef3a5bf74bc598c9b665ba7b8b7622e73ccc0a70b' 
  AND token = 'yiOBpKbJnqnTSbfXdQpM/4+60OD7XK6YzBaUCbG4Mjg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}