SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72edf388831e320917e11239fab394714a3bf645676431e5f20e678d7062ae56' 
  AND token = 'WQcSysjY2WAtiK35mvdsORqkruRr6MjJ6XbkIjW/aeE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}