SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef6fdf988d586443488f7157c6ace035330a9dbbaf5541f9e26f38d80ee8c6ff' 
  AND token = 'D89v6XqkGtVFLbsGSaVkXJTOcIm/nGtRTvDEuKyjtB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}