SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1f9c3cc83f6c08184e980f28f866b6ff589c7c42de9d021eb3366730eed7eda' 
  AND token = 'MqspjRK8YgBbGmOqiaxppn9Wdrs5KfGuvQeDX223+zE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}