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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fbfe5c57d4d137dfc6459e20f2554173d8e127d076d3c2f79537adfcf892ce3c' 
  AND token = 'DAt4BqBJKcEaVsqAlWuAnEaYpsVzrAaQsBgOFJn7rDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}