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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fd5630c844638cee052972fc3928ffc0b67b8193458e5ec4d9c5bbb0c7166ea' 
  AND token = '46Z3P+6XdwhAnsgdLd4Rp3hrON6zDpAxx9zYvqNc0Kw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}