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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c5cf8fb4e327e87eb310626aafff8a2f74515bd13fef5f0186c4198b73bf9de' 
  AND token = 'R5yyGQ75HF44a1xHD1GWdHCZ7E7Bzh7Oz4qgs8ZHBDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}