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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95583c282ce9d3b7370adf781e4e6949653d926f385b6cdb2ce4d96c07a5fa0c' 
  AND token = 'seAtvyH+RseHXQn/W9QJFon6SR3J8f4Gzkgya9aJNhQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}