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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16d61886f10911b3e97d26ed3e2d2541cafdb7c8c31692bb98992080d6e246f0' 
  AND token = 'y8KQRZFaOeZSHtFef6cUGGtaTpNWfroH3IW91EKtufM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}