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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20cf8222a7f5745f13e646d7703a548fd1523c0fabb11cf5a7c1e5c932b44107' 
  AND token = '3+BaQqwExYAkA7pdKupey/u31mFMcDxVcVCh87+qGsU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}