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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03c2171ddaa1c07bb1652b8ec5529e07511437027c4809a4229fc7cd8ce3be69' 
  AND token = 'L974nMbDrV0PtrQ+9Lp7E+fAWsxG6w21kgAWpiyfThs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}