SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46cee7c2abe9bfb41a060e405a7895fa007584f8a83aa4fb85ed081eca31ac83' 
  AND token = 'b9Oy5CtWcXNuZMKsDxPi90azEA4fPd/9RB2MkzmsgzY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}