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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b5cda19fb5a184a219f746eea41e0743317d3d3a41928f5e59a6fec777cfa58' 
  AND token = 'FPNlfA7Zo4H7A2inu+f/IUpnSDTXp5FNCDLAkFdtFQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}