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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3c3a8f654f6e1f8ec10ad824d43c3379f64c6b51f0af708c2d1f1ff987af230' 
  AND token = 'e2vF0pUoAPn+M87FjjTavsPZl52B2x5lG0ZhXP48PdI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}