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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d10ab819df941c60b1beec64bed6665f5ed0dd75b0d30823988bb45f206f481' 
  AND token = 'O/O26GsABtZ0y6LoZS3dHmFko1QuA5B1R7U2Daue9Es=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}