SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c42dce12ca1727e63f26ae603d41cb47f77e71c5bde251b4a8ae6afbbb0f753' 
  AND token = 'IV3i+EhGztEShyzP/0g4HQjs/v4AgzSqhvtpGmYW5r4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}