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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'daaa387ff6927dee7f261089547e20d6bab0bb2cdcb73087d38b07777e5a2045' 
  AND token = '1gHnsRwFmOiYkrmx6e4HFmIj2i9zEmlxmWK9l2itlEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}