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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05e03bca0284bb2210ce0e8cfb3e06ec610340659878258a65e2fb9a972329c5' 
  AND token = 'HnQ7Pc67S5+q17w5/OVZ0t4TDI38fduDSMLe1Gwk8uA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}