SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e23e0a7d94e5f94c3bc3e5705aff7fe188f1e5c7236cd359fedfe49d20826438' 
  AND token = 'kfaO1CzJTTlyCOt5LLNY98UeXjlpDhtQG4SYS9dty7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}