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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b1203e95c45e21c79ac3c206ef4707def33c6c440645edfa261e76909d73c78' 
  AND token = 'GC2iVFAGSEgobFKtv4p54RtkZHXkYcfx3qkyXIhbZJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}