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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de262b27cb4fa5717c08c17b05743359405fb824839803dbd500dd6293624adf' 
  AND token = 'TDXdpjkEQfmc6TXPtAq9EkKk14athdLC2caBDIWL/lA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}